Miniaturized capillary electrophoresis with amperometric detection: Fast separation and detection of bioactive amines

被引：19

作者：

Chu, QC ^{[1
]}

Guan, YQ ^{[1
]}

Geng, CH ^{[1
]}

Ye, JN ^{[1
]}

机构：

[1] E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China

来源：

ANALYTICAL LETTERS | 2006年 / 39卷 / 04期

基金：

中国国家自然科学基金;

关键词：

miniaturized capillary electrophoresis with amperometric detection; bioactive amine; tryptamine; tyramine;

D O I：

10.1080/00032710600611129

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel miniaturized analytical system for fast separation and detection of bioactive amines, based on the coupling of a micromachined capillary electrophoresis ( CE) system with a Cu amperometric detector ( CE-AD) is described. Tryptamine, tryptophan, and tyramine could be detected down to the 1.5 x 10(-6) x 5.8 x 10(-7) M level with linearity up to the 2.0 x 10(-4) M level examined. The injection-to-injection reproducibility for analytes in peak current ( RSD < 3.6%) and for migration times ( RSD < 1.4%) were excellent. While the concept of miniaturized separation/detection systems is presented within the framework of food samples, such devices should be attractive for fields such as environment and clinic as an alternative to conventional CE and mu-CE.

引用

页码：729 / 740

页数：12

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