Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study

被引:265
作者
Wu, Jian [1 ,2 ]
Liu, Jun [3 ]
Zhao, Xinguo [4 ]
Liu, Chengyuan [5 ]
Wang, Wei [2 ]
Wang, Dawei [6 ]
Xu, Wei [7 ]
Zhang, Chunyu [8 ]
Yu, Jiong [1 ]
Jiang, Bin [9 ]
Cao, Hongcui [1 ,10 ]
Li, Lanjuan [1 ]
机构
[1] Zhejiang Univ, Affiliated Hosp 1, Coll Med, State Key Lab Diag & Treatment Infect Dis,Natl Cl, 79 Qingchun Rd, Hangzhou 310003, Peoples R China
[2] First Peoples Hosp Yancheng City, Dept Lab Med, Yancheng, Peoples R China
[3] Jiangnan Univ, Peoples Hosp Wuxi 5, Dept Lab Med, Wuxi, Jiangsu, Peoples R China
[4] Jiangnan Univ, Peoples Hosp Wuxi 5, Dept Resp, Wuxi, Jiangsu, Peoples R China
[5] First Peoples Hosp Yancheng City, Dept Infect Dis, Yancheng, Peoples R China
[6] Second Peoples Hosp Yancheng City, Dept Infect Dis, Yancheng, Peoples R China
[7] Jiangsu Univ, Sch Med, Dept Prevent Med & Publ Hlth Lab Sci, Zhenjiang, Jiangsu, Peoples R China
[8] Second Peoples Hosp Yancheng City, Dept Lab Med, Yancheng, Peoples R China
[9] Cent Blood Stn Yancheng City, Dept Lab Med, Yancheng, Jiangsu, Peoples R China
[10] Zhejiang Prov Key Lab Diag & Treatment Aging & Ph, Hangzhou, Peoples R China
关键词
coronavirus disease 2019 (COVID-19); clinical characteristics; imported cases; pneumonia; WUHAN;
D O I
10.1093/cid/ciaa199
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. We aimed to report the clinical characteristics of imported cases of coronavirus disease 2019 (COVID-19) in Jiangsu Province. Methods. We retrospectively investigated the clinical, imaging, and laboratory characteristics of confirmed cases of COVID-19 with World Health Organization interim guidance in 3 grade IIIA hospitals of Jiangsu from 22 January to 14 February 2020. Realtime RT-PCR was used to detect the new coronavirus in respiratory samples. Results. Of the 80 patients infected with COVID-19, 41 were female, with a median age of 46.1 years. Except for 3 severe patients, the rest of the 77 patients exhibited mild or moderate symptoms. Nine patients were unconfirmed until a third nucleic acid test; 38 cases had a history of chronic diseases. The main clinical manifestations of the patients were fever and cough, which accounted for 63 (78.75%) and 51 (63.75%) cases, respectively. Only 3 patients (3.75%) showed liver dysfunction. Imaging examination showed that 55 patients (68.75%) showed abnormal density shadow and 25 cases (31.25%) had no abnormal density shadow in the parenchyma of both lungs. Currently, 21 cases have been discharged from the hospital, and no patient died. The average length of stay for discharged patients was 8 days. Conclusions. Compared with the cases in Wuhan, the cases in Jiangsu exhibited mild or moderate symptoms and no obvious gender susceptibility. The proportion of patients having liver dysfunction and abnormal CT imaging was relatively lower than that in Wuhan. Notably, infected patients may be falsely excluded based on 2 consecutively negative respiratory pathogenic nucleic acid test results.
引用
收藏
页码:706 / 712
页数:7
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