Pediatric Antibody Response to Community-Acquired Staphylococcus aureus Infection Is Directed to Panton-Valentine Leukocidin

被引：21

作者：

Brown, Eric L. ^{[1
]}

Bowden, M. Gabriela ^{[2
]}

Bryson, Rebecca S. ^{[1
]}

Hulten, Kristina G. ^{[3
,4
]}

Bordt, Andrea S. ^{[2
]}

Forbes, Andrea ^{[3
,4
]}

Kaplan, Sheldon L. ^{[3
,4
]}

机构：

[1] Univ Texas Houston, Ctr Infect Dis, Sch Publ Hlth, Houston, TX 77030 USA

[2] Texas A&M Univ, Inst Biosci & Technol, Ctr Extracellular Matrix Biol, Houston, TX USA

[3] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA

[4] Texas Childrens Hosp, Houston, TX 77030 USA

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2009年 / 16卷 / 01期

关键词：

FIBRINOGEN-BINDING PROTEIN; 3-YEAR SURVEILLANCE; IDENTIFICATION; CHILDREN; CLONE; GENE;

D O I：

10.1128/CVI.00360-08

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We examined the antibody responses of pediatric patients infected with community-associated Staphylococcus aureus isolates. The data show that patients infected with Panton-Valentine leukocidin (PVL)-positive strains developed a dominant immunoglobulin G anti-PVL antibody response that correlates with markers of inflammation.

引用

页码：139 / 141

页数：3

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