Droplet-based microreactors for the synthesis of magnetic iron oxide nanoparticles

被引：266

作者：

Frenz, Lucas ^{[1
]}

El Harrak, Abdeslam ^{[1
]}

Pauly, Matthias ^{[2
]}

Begin-Colin, Sylvie ^{[2
]}

Griffiths, Andrew D. ^{[1
]}

Baret, Jean-Christophe ^{[1
]}

机构：

[1] Univ Strasbourg, CNRS, ISIS, UMR 7006, F-67083 Strasbourg, France

[2] Univ Strasbourg, IPCMC, CNRS, UMR 7504, F-67034 Strasbourg 2, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 36期

关键词：

iron oxide; microfluidics; microreactors; nanoparticles; synthesis in droplets;

D O I：

10.1002/anie.200801360

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Microdroplets for nanoparticles: An extremely reliable method to create droplet pairs, based on hydrodynamic coupling of two spatially separated nozzles, has been developed. Droplets containing the reagents for the precipitation of iron oxide are electrocoalesced to synthesize iron oxide nanoparticles in a very fast (millisecond-scale) and reproducible reaction (see picture). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6817 / 6820

页数：4

共 29 条

[1] Synthesis of iron oxide nanoparticles in a microfluidic device: preliminary results in a coaxial flow millichannel [J].

Abou Hassan, Ali ;

Sandre, Olivier ;

Cabuil, Valerie ;

Tabeling, Patrick .

CHEMICAL COMMUNICATIONS, 2008, (15) :1783-1785

[2] Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels [J].

Ahn, Keunho ;

Agresti, Jeremy ;

Chong, Henry ;

Marquez, Manuel ;

Weitz, D. A. .

APPLIED PHYSICS LETTERS, 2006, 88 (26)

[3] Decompressing emulsion droplets favors coalescence [J].

Bremond, Nicolas ;

Thiam, Abdou R. ;

Bibette, Jerome .

PHYSICAL REVIEW LETTERS, 2008, 100 (02)

[4] Hydrothermal synthesis of monodisperse magnetite nanoparticles [J].

Daou, T. J. ;

Pourroy, G. ;

Begin-Colin, S. ;

Greneche, J. M. ;

Ulhaq-Bouillet, C. ;

Legare, P. ;

Bernhardt, P. ;

Leuvrey, C. ;

Rogez, G. .

CHEMISTRY OF MATERIALS, 2006, 18 (18) :4399-4404

[5] Targeted nanoparticles for cancer therapy [J].

Gu, Frank X. ;

Karnik, Rohit ;

Wang, Andrew Z. ;

Alexis, Frank ;

Levy-Nissenbaum, Etgar ;

Hong, Seungpyo ;

Langer, Robert S. ;

Farokhzad, Omid C. .

NANO TODAY, 2007, 2 (03) :14-21

[6]

Hung L. -H., 2007, Journal of Medical and Biological Engineering, V27, P1

[7] Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis [J].

Hung, LH ;

Choi, KM ;

Tseng, WY ;

Tan, YC ;

Shea, KJ ;

Lee, AP .

LAB ON A CHIP, 2006, 6 (02) :174-178

[8] Water in carbon dioxide microemulsions: An environment for hydrophiles including proteins [J].

Johnston, KP ;

Harrison, KL ;

Clarke, MJ ;

Howdle, SM ;

Heitz, MP ;

Bright, FV ;

Carlier, C ;

Randolph, TW .

SCIENCE, 1996, 271 (5249) :624-626

[9] Miniaturizing chemistry and biology in microdroplets [J].

Kelly, Bernard T. ;

Baret, Jean-Christophe ;

Taly, Valerie ;

Griffiths, Andrew D. .

CHEMICAL COMMUNICATIONS, 2007, (18) :1773-1788

[10]

Krishnadasan S, 2007, LAB CHIP, V7, P1434, DOI 10.1039/b711412e

← 1 2 3 →