Involvement of an Essential Gene, mviN, in Murein Synthesis in Escherichia coli

被引：71

作者：

Inoue, Azusa ^{[1
]}

Murata, Yoshimitsu ^{[2
]}

Takahashi, Hiroshi ^{[2
]}

Tsuji, Naoko ^{[1
]}

Fujisaki, Shingo ^{[2
]}

Kato, Jun-ichi ^{[1
]}

机构：

[1] Tokyo Metropolitan Univ, Dept Biol Sci, Grad Sch Sci, Tokyo 1920397, Japan

[2] Toho Univ, Fac Sci, Dept Biomol Sci, Chiba 2748510, Japan

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 21期

关键词：

D O I：

10.1128/JB.00551-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We isolated a temperature-sensitive mutant with a mutation in mviN, an essential gene in Escherichia coli. At the nonpermissive temperature, mviN mutant cells swelled and burst. An intermediate in murein synthesis, polyprenyl diphosphate-N-acetylmuramic acid-(pentapeptide)-N-acetyl-glucosamine, accumulated in mutant cells. These results indicated that MviN is involved in murein synthesis.

引用

页码：7298 / 7301

页数：4

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