Microwave dielectric resonator biosensor for aqueous glucose solution

被引:108
作者
Kim, Jongchul [1 ,2 ]
Babajanyan, Arsen [1 ,2 ]
Hovsepyan, Artur [1 ,2 ]
Lee, Kiejin [1 ,2 ]
Friedman, Barry [3 ]
机构
[1] Sogang Univ, Dept Phys, Seoul 121742, South Korea
[2] Sogang Univ, Interdisciplinary Program Integrated Biotechnol, Seoul 121742, South Korea
[3] Sam Houston State Univ, Dept Phys, Huntsville, TX 77341 USA
关键词
Dielectric resonators - Reflection - Glucose - Microwave resonators - Microwaves;
D O I
10.1063/1.2968115
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
We report a near-field microwave biosensor based on a dielectric resonator to detect glucose concentration. A microwave biosensor with a high Q dielectric resonator allows observation of the small variation of the glucose concentration by measuring the shift of the resonance frequency and the microwave reflection coefficient S-11. We observed the concentration of glucose with a detectable resolution up to 5 mg/ml at an operating frequency of about f =1.68 GHz. The change in the glucose concentration is directly related to the change in the reflection coefficient due to the electromagnetic interaction between the dielectric resonator and the glucose solution. (C) 2008 American Institute of Physics.
引用
收藏
页数:3
相关论文
共 14 条
[1]   Near-field scanning microwave probe based on a dielectric resonator [J].
Abu-Teir, M ;
Golosovsky, M ;
Davidov, D ;
Frenkel, A ;
Goldberger, H .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2001, 72 (04) :2073-2079
[2]  
[Anonymous], 1985, HDB CHEM PHYS
[3]  
[Anonymous], 2015, MICROWAVE ENG
[4]   Positioning and levitation media for the separation of biological cells [J].
Arnold, WM .
IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, 2001, 37 (05) :1468-1475
[5]   Sodium chloride sensing by using a near-field microwave microprobe [J].
Babajanyan, Arsen ;
Kim, Jongchul ;
Kim, Songhui ;
Lee, Kiejin ;
Friedman, Barry .
APPLIED PHYSICS LETTERS, 2006, 89 (18)
[6]   Glucose biosensors based on organic light-emitting devices structurally integrated with a luminescent sensing element [J].
Choudhury, B ;
Shinar, R ;
Shinar, J .
JOURNAL OF APPLIED PHYSICS, 2004, 96 (05) :2949-2954
[7]   Sensitive, label-free DNA diagnostics based on near-field microwave imaging [J].
Friedman, B ;
Gaspar, MA ;
Kalachikov, S ;
Lee, K ;
Levicky, R ;
Shen, G ;
Yoo, H .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (27) :9666-9667
[8]   Implanted electrochemical glucose sensors for the management of diabetes [J].
Heller, A .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 1999, 1 :153-175
[9]   Real-time chemical sensing of aqueous ethanol glucose mixtures [J].
McKee, JM ;
Johnson, BP .
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2000, 49 (01) :114-119
[10]   Glucose biosensing using an enzyme-coated microcantilever [J].
Subramanian, A ;
Oden, PI ;
Kennel, SJ ;
Jacobson, KB ;
Warmack, RJ ;
Thundat, T ;
Doktycz, MJ .
APPLIED PHYSICS LETTERS, 2002, 81 (02) :385-387