Switchable Motion of DNA on Solid Supports

被引：33

作者：

Elbaz, Johann ^{[1
]}

Tel-Vered, Ran ^{[1
]}

Freeman, Ronit ^{[1
]}

Yildiz, Huseyin Bekir ^{[1
]}

Willner, Itamar ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 01期

关键词：

aptamers; DNA; FRET; molecular devices; nanoparticles; IN-VITRO; LOGIC; APTAMER; MACHINE; PROTEIN; ENZYME; SELECTION; DNAZYME; RELEASE; COCAINE;

D O I：

10.1002/anie.200802905

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tracking the changes: The switchable translocation of a nucleic acid strand with a methylene blue (MB+) redox group on a DNA track associated with a surface can be triggered by adenosine monophosphate (AMP, green) and adenosine deaminase (purple, see picture); the latter converts AMP into inosine monophosphate (orange). The motion of the nucleic acid can be followed by the electrochemical, photo-electrochemical, and fluorescence signals. (Figure Presented). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：133 / 137

页数：5

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