Synthesis and antitumor activity of cannabigerol

被引：18

作者：

Baek, SH

Han, DS

Yook, CN

Kim, YC

Kwak, JS

机构：

[1] WONKWANG UNIV,DEPT CHEM,IKSAN 570749,SOUTH KOREA

[2] WONKWANG UNIV,DEPT ORAL ANAT,IKSAN 570749,SOUTH KOREA

[3] WONKWANG UNIV,DEPT HLTH HYG,WONKWANG PUBL HLTH JR COLL,IKSAN 570750,SOUTH KOREA

来源：

ARCHIVES OF PHARMACAL RESEARCH | 1996年 / 19卷 / 03期

关键词：

cannabigerol; antitumor activity; mouse skin melanoma cell;

D O I：

10.1007/BF02976895

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Cannabigerol(3) was synthesized and evaluated for its inhibitory activity against mouse skin melanoma cells. Cannabigerol displayed significant antitumor activity [inhibitory concentration (IC50)=31.31 mu g/mL] in vitro assay.

引用

页码：228 / 230

页数：3

共 13 条

[11] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS
MOSMANN, T
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) : 55 - 63
[12] RECENT CLINICAL-EXPERIENCE WITH DRONABINOL
PLASSE, TF
GORTER, RW
KRASNOW, SH
LANE, M
SHEPARD, KV
WADLEIGH, RG
[J]. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1991, 40 (03) : 695 - 700
[13] ANTI-EMETICS IN PATIENTS RECEIVING CHEMOTHERAPY FOR CANCER - RANDOMIZED COMPARISON OF DELTA-9-TETRAHYDROCANNABINOL AND PROCHLORPERAZINE
SALLAN, SE
CRONIN, C
ZELEN, M
ZINBERG, NE
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1980, 302 (03) : 135 - 138

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