Regioselective reduction of N-alkyl-3-sulfonyl glutarimides.: Synthesis of 3,4-dihydro-3-tosylpyridin-2-ones

被引：17

作者：

Chang, BR ^{[1
]}

Chen, CY ^{[1
]}

Chang, NC ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(02)00446-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of N-alkyl-3-sulfonyl glutarimides (1) with sodium hydride and then lithium aluminum hydride could gibe regioselective reduced hydroxy piperidones (5) which were further dehydrated to 3,4-dihydro-3-tosylpyridin-2-ones (6) in the presence of boron trifluoride. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：3233 / 3235

页数：3

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