The art of discovery in biophysical organic chemistry

被引：6

作者：

Kosower, EM ^{[1
]}

机构：

[1] Tel Aviv Univ, Sch Chem, IL-69978 Tel Aviv, Israel

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 2005年 / 83卷 / 09期

关键词：

art of discovery; solvent polarity parameter; charge-transfer complex; stable free radical; solvent effect oil spectra;

D O I：

10.1139/V05-120

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Observations made in the course of experiments on pyridinium salts led to important discoveries in physical organic chemistry. The way in which the discoveries were made is likened to art rather than goal-directed "cold logic". We can describe the art of discovery as in effort enhanced by practice and intuition to recognize novelty in a finding provide productive insight into its nature. We shall present some examples, and describe what happened after finding all unexpected light absorption band, a surprising solvent effect on spectra, and an unexpectedly stable and beautiful small organic radical.

引用

页码：1207 / 1211

页数：5

共 18 条

[11] ADDITIONS TO PYRIDINIUM RINGS .1. 1-METHYLPYRIDINIUM IODIDE [J].

KOSOWER, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (14) :3883-3885

[12] THE EFFECT OF SOLVENT ON SPECTRA .3. THE USE OF Z-VALUES IN CONNECTION WITH KINETIC DATA [J].

KOSOWER, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (13) :3267-3270

[13] THE EFFECT OF SOLVENT ON SPECTRA .1. A NEW EMPIRICAL MEASURE OF SOLVENT POLARITY - Z-VALUES [J].

KOSOWER, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (13) :3253-3260

[14]

KOSOWER EM, 1965, TETRAHEDRON LETT, P4481

[15] THE EFFECT OF SOLVENT ON SPECTRA .2. CORRELATION OF SPECTRAL ABSORPTION DATA WITH Z-VALUES [J].

KOSOWER, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (13) :3261-3267

[16]

KOWOSER EM, 1962, MOL BIOCH

[17]

Reichardt C., 2003, SOLVENTS SOLVENT EFF

[18] FORMATION OF STABLE FREE RADICALS ON ELECTROREDUCTION OF N-ALKYLPYRIDINIUM SALTS [J].

SCHWARZ, WM ;

SHAIN, I ;

KOSOWER, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (14) :3164-&

← 1 2 →