Ellagitannins from Lagerstroemia speciosa as activators of glucose transport in fat cells

被引：66

作者：

Hayashi, T

Maruyama, H

Kasai, R

Hattori, K

Takasuga, S

Hazeki, O

Yamasaki, K

Tanaka, T

机构：

[1] Hiroshima Univ, Inst Pharmaceut Sci, Fac Med, Minami Ku, Hiroshima 7348551, Japan

[2] Nagasaki Univ, Fac Pharmaceut Sci, Nagasaki 852, Japan

来源：

PLANTA MEDICA | 2002年 / 68卷 / 02期

关键词：

D O I：

10.1055/s-2002-20251

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Glucose transport enhancers were searched for in Lagerstroemia speciosa, a Philippine local herbal medicine used for diabetes mellitus. Bioassay-guided fractionation of the aqueous acetone extract of the leaves afforded three active ellagitannins, lagerstroemin, flosin B and reginin A, identified by NMR and optical rotation. These compounds increased glucose uptake of rat adipocytes, and could be responsible for lowering the blood glucose level.

引用

页码：173 / 175

页数：3