Stille couplings catalytic in tin: A "Sn-F" approach

被引：37

作者：

Maleczka, RE ^{[1
]}

Gallagher, WP ^{[1
]}

机构：

[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 26期

关键词：

D O I：

10.1021/ol016792z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new tin recycling method for Stille couplings catalytic in tin is reported. PMHS made hypercoordinate by KF(aq) allows Me3SnH to be efficiently recycled during a Pd(0)-catalyzed hydrostannation/Stille cascade. Relative to previously disclosed protocols, reaction times are shorter and because this process is believed to proceed through a Me3SnF intermediate the hazards and problems associated with trimethyltins are also diminished.

引用

页码：4173 / 4176

页数：4

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