Nasogastric intubation after abdominal surgery - A meta-analysis of recent literature

被引:29
作者
Vermeulen, H
Storm-Versloot, MN
Busch, ORC
Ubbink, DT
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Surg, NL-1100 DE Amsterdam, Netherlands
[2] Acad Med Ctr, Dept Clin Epidemiol & Biostat, Amsterdam, Netherlands
关键词
D O I
10.1001/archsurg.141.3.307
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: To determine whether refraining from nasogastric intubation (NGI) in patients after abdominal surgery will result in the same therapeutic effectiveness as using NGI. Data Source: We identified randomized trials from the Cochrane Central Register of Controlled Trials published between January 1990 and January 2005. Study Selection: Two of us independently selected trials based on randomization, abdominal surgery in patients, early vs late removal of the NGI, and reporting at least I of the following end points: hospital stay, gastrointestinal function, and postoperative complications. Data Extraction: Two of us independently performed trial quality assessment and data extraction. Trials were judged using a structured list that included factors relating to internal and external validity. Data were entered and analyzed by means of dedicated software from the Cochrane Collaboration. Data Synthesis: Seventeen randomized trials met the inclusion criteria. Meta-analysis showed that NGI does not offer any clinically relevant benefits for patients after abdominal surgery, such as recovery of gastrointestinal function or reduction of postoperative complications (relative risk, 1.18; 95% confidence interval, 0.98-1.42). Moreover, NGI showed some undesired effects, such as discomfort (in 609'o of the NGI patients) and a later return to a liquid diet (weighted mean difference, 0.65 days; 95% confidence interval, 0.38-0.92 days) or a regular diet, whereas hospital stay was not shortened. Conclusions: Routine NGI seems to serve no beneficial purpose and may even be harmful in patients after modern abdominal surgery; also, it is uncomfortable. Therefore, NGI is recommended only as a therapeutic approach.
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页码:307 / 314
页数:8
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