Hyperbranched polymers for controlled release of cisplatin

被引:52
作者
Haxton, Katherine J. [1 ,2 ]
Burt, Helen M. [1 ]
机构
[1] Univ British Columbia, Fac Pharmaceut Sci, Vancouver, BC V6T 1Z3, Canada
[2] Univ Keele, Sch Phys & Geog Sci, Keele ST5 5BG, Staffs, England
基金
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词
D O I
10.1039/b809949a
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Hyperbranched polymers based on a polyether and polyester have been modified and used as macromolecular ligands for the anticancer drug cisplatin, giving controlled release of the drug over 7 days.
引用
收藏
页码:5872 / 5875
页数:4
相关论文
共 16 条
[11]   Synthesis and characterization of AP5346, a novel polymer-linked diaminocyclohexyl platinum chemotherapeutic agent [J].
Sood, Paul ;
Thurmond, K. Bruce, II ;
Jacob, Jeremy E. ;
Waller, Lynda K. ;
Silva, George O. ;
Stewart, Donald R. ;
Nowotnik, David P. .
BIOCONJUGATE CHEMISTRY, 2006, 17 (05) :1270-1279
[12]  
Sunder A, 2000, ADV MATER, V12, P235, DOI 10.1002/(SICI)1521-4095(200002)12:3<235::AID-ADMA235>3.3.CO
[13]  
2-P
[14]   Multifunctional nanocarriers [J].
Torchilin, Vladimir P. .
ADVANCED DRUG DELIVERY REVIEWS, 2006, 58 (14) :1532-1555
[15]   Novel functional hyperbranched polyether polyols as prospective drug delivery systems [J].
Tziveleka, LA ;
Kontoyianni, C ;
Sideratou, Z ;
Tsiourvas, D ;
Paleos, CM .
MACROMOLECULAR BIOSCIENCE, 2006, 6 (02) :161-169
[16]   Structure-to-properties relationship of aliphatic hyperbranched polyesters [J].
Zagar, Ema ;
Huskic, Miroslav ;
Zigon, Majda .
MACROMOLECULAR CHEMISTRY AND PHYSICS, 2007, 208 (13) :1379-1387