Evaluation of binding and origins of specificity of 9-ethyladenine imprinted polymers

被引:225
作者
Spivak, D [1 ]
Gilmore, MA [1 ]
Shea, KJ [1 ]
机构
[1] UNIV CALIF IRVINE, DEPT CHEM, IRVINE, CA 92697 USA
关键词
D O I
10.1021/ja963510v
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An investigation of 9-ethyladenine (9-EA) imprinted polymers has provided insight into the origins of binding and recognition by imprinted polymers. Porogens and polymerization temperature are important variables during the polymerization. Factors that influence rebinding of the 9-EA imprinted polymer include pH and utilization of the porogen as mobile phase. Finally, quantitative structure-binding relationship studies elicited the substructures of 9-EA primarily responsible for creating the binding sites within the polymers.
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页码:4388 / 4393
页数:6
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