Domino metathesis of 2-azanorbornenones:: A new strategy for the enatioselective synthesis of 1-azabicyclic compounds

被引：57

作者：

Arjona, O ^{[1
]}

Csáky, AG ^{[1
]}

Medel, R ^{[1
]}

Plumet, J ^{[1
]}

机构：

[1] Univ Complutense, Fac Quim, Dept Quim Organ, Madrid, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 04期

关键词：

D O I：

10.1021/jo016000e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Domino metathesis of N-alkylated derivatives of (1S)-2-azanorborn-5-en-3-one allowed for the enantioselective synthesis of pyrrolizidine, quinolizidine, pyrrolidinoazepine, and pyrrolidinoazocine derivatives in a straightforward process.

引用

页码：1380 / 1383

页数：4

共 25 条

[1]

Angiolini M, 2000, EUR J ORG CHEM, V2000, P2571

[2]

Arisawa M, 1997, SYNLETT, P1179

[3]

Brandt P, 2000, SYNLETT, P1092

[4]

Choi TL, 2001, ANGEW CHEM INT EDIT, V40, P1277, DOI 10.1002/1521-3773(20010401)40:7<1277::AID-ANIE1277>3.3.CO

[5]

2-5

[6]

CORDELL GA, 2001, ALKALOIDS, V55

[7] Efficient stereoselective syntheses of piperidine, pyrrolidine, and indolizidine alkaloids [J].

Enders, D ;

Thiebes, C .

PURE AND APPLIED CHEMISTRY, 2001, 73 (03) :573-578

[8]

Fürstner A, 2000, ANGEW CHEM INT EDIT, V39, P3012

[9] Recent advances in olefin metathesis and its application in organic synthesis [J].

Grubbs, RH ;

Chang, S .

TETRAHEDRON, 1998, 54 (18) :4413-4450

[10] Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics [J].

Hanessian, S ;

McNaughtonSmith, G ;

Lombart, HG ;

Lubell, WD .

TETRAHEDRON, 1997, 53 (38) :12789-12854

← 1 2 3 →