Cloning and sequence analysis of the fimbriae associated protein (fap) gene from Actinobacillus actinomycetemcomitans

被引：21

作者：

Ishihara, K ^{[1
]}

Honma, K ^{[1
]}

Miura, T ^{[1
]}

Kato, T ^{[1
]}

Okuda, K ^{[1
]}

机构：

[1] TOKYO DENT COLL,DEPT MICROBIOL,MIHAMA KU,CHIBA 261,JAPAN

来源：

MICROBIAL PATHOGENESIS | 1997年 / 23卷 / 02期

关键词：

Actinobacillus actinomycetemcomitans; fimbriae associated protein; adherence; fimbriae expression;

D O I：

10.1006/mpat.1997.0137

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Fimbrial-associated protein, an attachment factor of Actinobacillus actinomycetemcomitans, was genetically analysed by cloning. The plasmid obtained was found to harbor a 1.7kb fragment which contained a 228bp open reading frame encoding 76 amino acids (7.970kDa). The fimbriae associated protein gene (fap) was strongly expressed in fimbriated A. actinomycetemcomitans 310a but not in non-fimbriated strains. (C) 1997 Academic Press Limited.

引用

页码：63 / 69

页数：7