A method and technical equipment for an acute human trial to evaluate retinal implant technology

被引：51

作者：

Hornig, Ralf ^{[1
]}

Laube, Thomas ^{[2
]}

Walter, Peter ^{[3
]}

Velikay-Parel, Michaela ^{[4
]}

Bornfeld, Norbert ^{[2
]}

Feucht, Matthias ^{[5
]}

Akguel, Harun ^{[2
]}

Roessler, Gernot ^{[3
]}

Alteheld, Nils ^{[3
]}

Notarp, Dietmar Luetke ^{[1
]}

Wyatt, John ^{[6
,7
]}

Richard, Gisbert ^{[5
]}

机构：

[1] IIP Technol GmbH, Bonn, Germany

[2] Duisburg Essen Univ, Dept Ophthalmol, Essen, Germany

[3] Rhein Westfal TH Aachen, Dept Ophthalmol, Aachen, Germany

[4] Univ Vienna, Dept Ophthalmol, Vienna, Austria

[5] Univ Hamburg, Dept Ophthalmol, Hamburg, Germany

[6] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[7] MIT, Elect Res Lab, Cambridge, MA 02139 USA

来源：

JOURNAL OF NEURAL ENGINEERING | 2005年 / 2卷 / 01期

关键词：

D O I：

10.1088/1741-2560/2/1/014

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This paper reports on methods and technical equipment to investigate the epiretinal stimulation of the retina in blind human subjects in acute trials. Current is applied to the retina through a thin, flexible microcontact film (microelectrode array) with electrode diameters ranging from 50 to 360 mu m. The film is mounted in a custom-designed surgical tool that is hand-held by the surgeon during stimulation. The eventual goal of the work is the development of a chronically implantable retinal prosthesis to restore a useful level of vision to patients who are blind with outer retinal degenerations, specifically retinitis pigmentosa and macular degeneration.

引用

页码：S129 / S134

页数：6

共 23 条

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