A model of phototransduction by the human circadian system

被引：275

作者：

Rea, MS ^{[1
]}

Figueiro, MG ^{[1
]}

Bullough, JD ^{[1
]}

Bierman, A ^{[1
]}

机构：

[1] Rensselaer Polytech Inst, Lighting Res Ctr, Troy, NY 12180 USA

来源：

BRAIN RESEARCH REVIEWS | 2005年 / 50卷 / 02期

关键词：

melatonin suppression; melanopsin; spectral sensitivity; retinal ganglion cell; spectral opponency; retina; photoreceptor; circadian rhythm;

D O I：

10.1016/j.brainresrev.2005.07.002

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The absolute and spectral sensitivities to light by the human cireadian system, measured through melatonin Suppression or phase shifting response, are beginning to emerge after a quarter century of active research. The present paper Outlines a hypothesized model of human circadian phototransduction that is consistent with the known neuroanatomy and physiology of the human Visual and circadian systems. Spectral opponency is fundamental to file model, providing a parsimonious explanation of some recently published data. The proposed model offers a framework for hypothesis testing and subsequent discussion Of file practical aspects of architectural lighting with respect to light and health. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：213 / 228

页数：16

共 105 条

[1] Responses of neurones of the rat suprachiasmatic nucleus to retinal illumination under photopic and scotopic conditions
Aggelopoulos, NC
Meissl, H
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 2000, 523 (01): : 211 - 222
[2] EFFECT OF BLEACHING AND BACKGROUNDS ON PUPIL SIZE
ALPERN, M
OHBA, N
[J]. VISION RESEARCH, 1972, 12 (05) : 943 - &
[3] [Anonymous], 1997, Lighting Research and Technology, DOI DOI 10.1177/14771535970290030501
[4] Minimum light intensity required to suppress nocturnal melatonin concentration in human saliva
Aoki, H
Yamada, N
Ozeki, Y
Yamane, H
Kato, N
[J]. NEUROSCIENCE LETTERS, 1998, 252 (02) : 91 - 94
[5] The murine cone photoreceptor: A single cone type expresses both S and M opsins with retinal spatial patterning
Applebury, ML
Antoch, MP
Baxter, LC
Chun, LLY
Falk, JD
Farhangfar, F
Kage, K
Krzystolik, MG
Lyass, LA
Robbins, JT
[J]. NEURON, 2000, 27 (03) : 513 - 523
[6] Melanopsin retinal ganglion cells receive bipolar and amacrine cell synapses
Belenky, MA
Smeraski, CA
Provencio, I
Sollars, PJ
Pickard, GE
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 2003, 460 (03) : 380 - 393
[7] BERMAN SM, 1992, J ILLUM ENG SOC, V21, P3
[8] Phototransduction by retinal ganglion cells that set the circadian clock
Berson, DM
Dunn, FA
Takao, M
[J]. SCIENCE, 2002, 295 (5557) : 1070 - 1073
[9] Strange vision: ganglion cells as circadian photoreceptors
Berson, DM
[J]. TRENDS IN NEUROSCIENCES, 2003, 26 (06) : 314 - 320
[10] Resetting of circadian melatonin and cortisol rhythms in humans by ordinary room light
Boivin, DB
Czeisler, CA
[J]. NEUROREPORT, 1998, 9 (05) : 779 - 782

← 1 2 3 4 5 6 7 8 9 10 →