n-3 fatty acids: Antiatherosclerotic effects

被引：40

作者：

De Caterina, R

Zampolli, A

机构：

[1] Univ G DAnnunzio, Dept Cardiol, Chieti, Italy

[2] CNR, Inst Clin Physiol, I-56100 Pisa, Italy

来源：

LIPIDS | 2001年 / 36卷

关键词：

D O I：

10.1007/s11745-001-0685-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The low incidence of cardiovascular disease associated epidemiologically with high consumption of food rich in n-3 fatty acids suggests the possibility that part of the beneficial cardiovascular effects of these natural substances may be due to a reduction of atherosclerosis. This has been recently confirmed in autoptic data and in at least one prospective trial evaluating the progression of coronary atherosclerosis in humans. This paper reviews published literature on n-3 fatty acids and atherosclerosis in animal models and in humans and in vitro experimental data yielding suport to the hypothesis of antiatherosclerotic effects of these substances.

引用

收藏

页码：S69 / S78

页数：10

相关论文

共 90 条

[1] EFFECT OF A HIGH-FAT CHOLESTEROL DIET WITH OR WITHOUT EICOSAPENTAENOIC ACID ON PLASMA-LIPIDS, LIPOPROTEINS AND LIPID TRANSFER PROTEIN-ACTIVITY IN THE MARMOSET [J].

ABBEY, M ;

CLIFTON, PM ;

MCMURCHIE, EJ ;

MCINTOSH, GH ;

NESTEL, PJ .

ATHEROSCLEROSIS, 1990, 81 (03) :163-174

[2] Concentration of serum lipids and aortic lesion size in female and male apo E-deficient mice fed docosahexaenoic acid [J].

Adan, Y ;

Shibata, K ;

Ni, WH ;

Tsuda, Y ;

Sato, M ;

Ikeda, I ;

Imaizumi, K .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1999, 63 (02) :309-313

[3] n-3 Polyunsaturated fatty acids and the cardiovascular system [J].

Angerer, P ;

von Schacky, C .

CURRENT OPINION IN LIPIDOLOGY, 2000, 11 (01) :57-63

[4] DOUBLE-BLIND, RANDOMIZED, CONTROLLED TRIAL OF FISH OIL SUPPLEMENTS IN PREVENTION OF RECURRENCE OF STENOSIS AFTER CORONARY ANGIOPLASTY [J].

BAIRATI, I ;

ROY, L ;

MEYER, F .

CIRCULATION, 1992, 85 (03) :950-956

[5]

BANG HO, 1976, ACTA MED SCAND, V200, P69

[6] Dietary fish oil - Influence on lesion regression in the porcine model of atherosclerosis [J].

Barbeau, ML ;

Klemp, KF ;

Guyton, JR ;

Rogers, KA .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1997, 17 (04) :688-694

[7] Dietary ω-3, ω-6, and ω-9 unsaturated fatty acids and growth factor and cytokine gene expression in unstimulated and stimulated monocytes -: A randomized volunteer study [J].

Baumann, KH ;

Hessel, F ;

Larass, I ;

Müller, T ;

Angerer, P ;

Kiefl, R ;

von Schacky, C .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1999, 19 (01) :59-66

[8] CAN SUPPLEMENTATION OF DIET WITH OMEGA-3 POLYUNSATURATED FATTY-ACIDS REDUCE CORONARY ANGIOPLASTY RESTENOSIS RATE [J].

BELLAMY, CM ;

SCHOFIELD, PM ;

FARAGHER, EB ;

RAMSDALE, DR .

EUROPEAN HEART JOURNAL, 1992, 13 (12) :1626-1631

[9]

Boerboom LE, 1997, CIRCULATION, V96, P968

[10] Mouse models of atherosclerosis [J].

Breslow, JL .

SCIENCE, 1996, 272 (5262) :685-688

← 1 2 3 4 5 6 7 8 9 →