Chiral aminophosphine-oxazoline auxiliaries applied to copper-catalysed enantioselective 1,4-additions to enones

被引：15

作者：

Blanc, C ^{[1
]}

Agbossou-Niedercorn, F ^{[1
]}

机构：

[1] ENSCL, CNRS, Catalyse Lab, UMR 8010, F-59652 Villeneuve Dascq, France

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 05期

关键词：

D O I：

10.1016/j.tetasy.2004.01.002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of chiral aminophosphine-oxazoline auxiliaries has been prepared and applied in the copper-catalysed 1,4-addition of diethylzinc to enones. The addition products are obtained quantitatively in up to 67% ee. The most efficient ligand of the series is based on L-indoline carboxylic acid and L-valinol. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：757 / 761

页数：5

共 50 条

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