The Tol proteins of Escherichia coli and their involvement in the uptake of biomolecules and outer membrane stability

被引：106

作者：

Lazzaroni, JC ^{[1
]}

Germon, P ^{[1
]}

Ray, MC ^{[1
]}

Vianney, A ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS,UMR 5577, INSA, Unite Microbiol & Genet, F-69622 Villeurbanne, France

来源：

FEMS MICROBIOLOGY LETTERS | 1999年 / 177卷 / 02期

关键词：

TolQ; TolR; TolA; TolB; Pal; outer membrane stability; periplasm; uptake of macromolecule;

D O I：

10.1016/S0378-1097(99)00293-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Tol proteins of Escherichia coli are involved in outer membrane stability. They are also required for the uptake of the group A colicins and the translocation of filamentous phage DNA into the cytoplasm. The tol-pal genes constitute two operons in the E. coli genome, orf1tolQRA and tolBpalorf2. The TolQ TolR TolA proteins form a complex in the cytoplasmic membrane, while TolB and Pal interact near the outer membrane. Most of the amino acid residues of TolA, TolB, TolR and Pal are localized in the periplasm. Recent advances in the knowledge of interactions of Tol-Pal proteins with other envelope components, or with group A colicins, are presented, together with current hypotheses about the role of the Tol proteins in outer membrane stability. (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：191 / 197

页数：7

共 33 条

[11] Lipopolysaccharides and divalent cations are involved in the formation of an assembly-competent intermediate of outer-membrane protein PhoE of E-coli [J].

deCock, H ;

Tommassen, J .

EMBO JOURNAL, 1996, 15 (20) :5567-5573

[12] The permeability of the wall fabric of Escherichia coli and Bacillus subtilis [J].

Demchick, P ;

Koch, AL .

JOURNAL OF BACTERIOLOGY, 1996, 178 (03) :768-773

[13] TolA central domain interacts with Escherichia coli porins [J].

Derouiche, R ;

Gavioli, M ;

Benedetti, H ;

Prilipov, A ;

Lazdunski, C ;

Lloubes, R .

EMBO JOURNAL, 1996, 15 (23) :6408-6415

[14] Folding of a bacterial outer membrane protein during passage through the periplasm [J].

Eppens, EF ;

Nouwen, N ;

Tommassen, J .

EMBO JOURNAL, 1997, 16 (14) :4295-4301

[15] Mutational analysis of the Escherichia coli K-12 TolA N-terminal region and characterization of its TolQ-interacting domain by genetic suppression [J].

Germon, P ;

Clavel, T ;

Vianney, A ;

Portalier, R ;

Lazzaroni, JC .

JOURNAL OF BACTERIOLOGY, 1998, 180 (24) :6433-6439

[16] ROLE OF THE TONB AMINO-TERMINUS IN ENERGY TRANSDUCTION BETWEEN MEMBRANES [J].

JASKULA, JC ;

LETAIN, TE ;

ROOF, SK ;

SKARE, JT ;

POSTLE, K .

JOURNAL OF BACTERIOLOGY, 1994, 176 (08) :2326-2338

[17] A SEQUENCE-SPECIFIC FUNCTION FOR THE N-TERMINAL SIGNAL-LIKE SEQUENCE OF THE TONB PROTEIN [J].

KARLSSON, M ;

HANNAVY, K ;

HIGGINS, CF .

MOLECULAR MICROBIOLOGY, 1993, 8 (02) :379-388

[18] Colicin import into Escherichia coli cells [J].

Lazdunski, CJ ;

Bouveret, E ;

Rigal, A ;

Journet, L ;

Lloubès, R ;

Bénédetti, H .

JOURNAL OF BACTERIOLOGY, 1998, 180 (19) :4993-5002

[19] TRANSMEMBRANE ALPHA-HELIX INTERACTIONS ARE REQUIRED FOR THE FUNCTIONAL ASSEMBLY OF THE ESCHERICHIA-COLI TOL COMPLEX [J].

LAZZARONI, JC ;

VIANNEY, A ;

POPOT, JL ;

BENEDETTI, H ;

SAMATEY, F ;

LAZDUNSKI, C ;

PORTALIER, R ;

GELI, V .

JOURNAL OF MOLECULAR BIOLOGY, 1995, 246 (01) :1-7

[20] THE EXCC GENE OF ESCHERICHIA-COLI K-12 REQUIRED FOR CELL-ENVELOPE INTEGRITY ENCODES THE PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN (PAL) [J].

LAZZARONI, JC ;

PORTALIER, R .

MOLECULAR MICROBIOLOGY, 1992, 6 (06) :735-742

← 1 2 3 4 →