Catalytic asymmetric synthesis of optically active alkenes by palladium-catalysed asymmetric reduction of racemic allylic esters with formic acid

被引：23

作者：

Hayashi, T

Kawatsura, M

Iwamura, H

Yamaura, Y

Uozumi, Y

机构：

[1] Department of Chemistry, Faculty of Science, Kyoto University, Sakyo

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 15期

关键词：

D O I：

10.1039/cc9960001767

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric reduction of racemic allyl esters, e.g. methyl 1-vinyl-1,2,3,4-tetrahydronaphth-1-yl carbonate, which contain two different alkyl groups at the alpha-position, with formic acid in the presence of 1 mol% of palladium catalyst coordinated with (R)-3-diphenylphosphino-3'methoxy-4,4'-biphenanthryl [(R)-MOP-phen] ligand gives optically active terminal alkenes in up to 93% ee.

引用

页码：1767 / 1768

页数：2

共 14 条

[11]

Tsuji J, 1996, SYNTHESIS-STUTTGART, P1

[12] SYNTHESIS OF OPTICALLY-ACTIVE 2-(DIARYLPHOSPHINO)-1,1'-BINAPHTHYLS, EFFICIENT CHIRAL MONODENTATE PHOSPHINE-LIGANDS [J].