Study on the effect of electrostatic interaction on core-shell nanoparticles preparation with microemulsion technique

The routine method for preparation of silica core-shell nanoparticles (NPs) is to carry out nucleation and shell coating through the hydrolysis of silane in water in oil (W/O) microemulsion to form three-dimensional netted silica shell. We found that electrostatic interaction of the core materials with shell materials would determine whether the stable core-shell silica NPs formed or not. The traditional important factors such as molecular weight of core materials or the thickness of the shell have no obvious relationship with it. And the stability of the core-shell silica NPs can be improved after changing the electric charge polarity by regulating the experiment condition of relevant materials if some core materials cannot be doped inside to form the stable core-shell silica NPs based on the traditional method, which provided experimental and theoretic foundation for preparation and application of the core-shell silica NPs.