Cephalocyclidin A, a novel pentacyclic alkaloid from Cephalotaxus harringtonia var. nana

被引：28

作者：

Kobayashi, J ^{[1
]}

Yoshinaga, M

Yoshida, N

Shiro, M

Morita, H

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Rigaku Corp, Xray Res Lab, Akishima, Tokyo 1968666, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 07期

关键词：

D O I：

10.1021/jo016327f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel alkaloid with an unprecedented fused-pentacyclic skeleton and six-consecutive asymmetric centers, cephalocyclidin A (1), has been isolated from the fruits of Cephalotaxus harringtonia var. nana, and the structure was elucidated on the basis of spectroscopic data. The relative and absolute stereochemistry of I was determined by a combination of NOESY correlations, X-ray crystallographic data, and the exciton chirality method.

引用

页码：2283 / 2286

页数：4

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