Bismuth nitrate pentahydrate:: a new and environmentally benign reagent for guanidylation of N-benzoylthioureas

被引：49

作者：

Cunha, S ^{[1
]}

de Lima, BR ^{[1
]}

de Souza, AR ^{[1
]}

机构：

[1] Univ Fed Goias, Inst Quim, BR-74001970 Goiania, Go, Brazil

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 01期

关键词：

bismuth; acylguanidines; thioureas;

D O I：

10.1016/S0040-4039(01)02067-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bismuth nitrate-mediated guanidylation of N-benzoylthioureas was studied. This salt proved to be an effective guanylating reagent and allowed the obtention of N-benzoyl-guanidines in good yields. The methodology described is a promising alternative to the use of toxic HgCl2 in the synthesis of polysubstituted guanidines. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：49 / 52

页数：4

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