Isolation and chemotaxonomic significance of tuberostemospironine-type alkaloids from Stemona tuberosa

被引：43

作者：

Jiang, RW

Hon, PM

Xu, YT

Chan, YM

Xu, HX

Shaw, PC

But, PPH

机构：

[1] Chinese Univ Hong Kong, Inst Chinese Med, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Biol, Shatin, Hong Kong, Peoples R China

[3] Hong Kong Jockey Club Inst Chinese Med, Shatin, Hong Kong, Peoples R China

[4] Chinese Univ Hong Kong, Dept Biochem, Shatin, Hong Kong, Peoples R China

来源：

PHYTOCHEMISTRY | 2006年 / 67卷 / 01期

关键词：

Stemona tuberosa; Croomia; Stemonaceae; croomine; 6; alpha-hydroxycroomine; trnL sequence;

D O I：

10.1016/j.phytochem.2005.10.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An alkaloid named 6 alpha-hydroxycroomine (1) as well as the known croomine (2), both belonging to the tuberostemospironine-alkaloid type, were isolated from Stemona tuberosa as the major components. The structure of 1 was elucidated through extensive spectroscopic analyses. Comparison of the HPLC profiles of the total alkaloids and the crude methanol extract showed that both compounds are naturally occurring. The first isolation of 1 and 2 from S. tuberosa has chemotaxonomic significance, confirming the close relationship between Stemona and Croomia. The trnL sequences of plants from the four genera of Stemonaceae cluster together as a clade, further lending support to retaining them in a single family. (c) 2005 Published by Elsevier Ltd.

引用

页码：52 / 57

页数：6

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