The relationship between new variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy

被引：15

作者：

Knight, R

机构：

[1] Western Gen Hosp, Natl CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland

[2] Univ Edinburgh, Dept Clin Neurosci, Edinburgh EH8 9YL, Midlothian, Scotland

来源：

VOX SANGUINIS | 1999年 / 76卷 / 04期

关键词：

D O I：

10.1159/000031052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Creutzfeldt-Jakob disease (CJD) has been transmitted in the laboratory and also by iatrogenic accident. However, research has failed to find evidence that its most common form (sporadic CJD) is a natural infection and, in particular, that there is a causal link with scrapie, Bovine spongiform encephalopathy (BSE) probably resulted from scrapie infection in cattle food. In the wake of the BSE epidemic, a novel clinico-pathological form of CJD has been recognized: new va riant CJD (nvCJD). This paper reviews the relationship between nvCJD and BSE and presents the accumulated evidence supporting the view that nvCJD resulted from BSE contamination of human food.

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收藏

页码：203 / 208

页数：6

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