Dendrimer-scaffold-based electron-beam patterning of biomolecules

被引:29
作者
Bhatnagar, P
Mark, SS
Kim, I
Chen, HY
Schmidt, B
Lipson, M
Batt, CA
机构
[1] Cornell Univ, Dept Biomed Engn, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Microbiol, Ithaca, NY 14853 USA
[3] Cornell Univ, Dept Microbiol, Ithaca, NY 14853 USA
[4] Cornell Univ, Dept Elect & Comp Engn, Ithaca, NY 14853 USA
关键词
D O I
10.1002/adma.200501170
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A layer-by-layer approach for patterning biomolecules on dendrimer scaffolds using electron-beam lithography has been developed (see Figure). A self-assembled poly(ethylene glycol) monolayer is patterned with aldehyde-terminated polyamidoamine dendrimers to allow the covalent immobilization of aminated oligonucleotide probes.
引用
收藏
页码:315 / +
页数:6
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