Ring opening cross-metathesis on solid support

被引：50

作者：

Cuny, GD

Cao, JR

Hauske, JR

机构：

[1] Sepracor Inc., Marlborough, MA 01752-7231

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(97)01144-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring opening cross-metathesis (ROM) of bicyclic alkenes with terminal aryl alkenes on solid support was accomplished. A select group of resin-bound bicyclic alkenes underwent highly regioselective ROM with electron rich styrenes. The influence of both electronic and steric factors on regioselectivity was examined. (C) 1997 Elsevier Science Ltd.

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页码：5237 / 5240

页数：4

相关论文

共 15 条

[1]

BLECHERT S, 1996, ANGEW CHEM INT EDIT, V35, P411

[2] BROP - A NEW REAGENT FOR COUPLING N-METHYLATED AMINO-ACIDS [J].

COSTE, J ;

DUFOUR, MN ;

PANTALONI, A ;

CASTRO, B .

TETRAHEDRON LETTERS, 1990, 31 (05) :669-672

[3] HIGHLY SELECTIVE CROSS-METATHESIS OF TERMINAL OLEFINS [J].

CROWE, WE ;

ZHANG, ZJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (23) :10998-10999

[4] Design, synthesis, and evaluation of small-molecule libraries [J].

Ellman, JA .

ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) :132-143

[5] RING-CLOSING METATHESIS AND RELATED PROCESSES IN ORGANIC-SYNTHESIS [J].

GRUBBS, RH ;

MILLER, SJ ;

FU, GC .

ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (11) :446-452

[6] A SOLID-PHASE CBZ CHLORIDE EQUIVALENT - A NEW MATRIX SPECIFIC LINKER [J].

HAUSKE, JR ;

DORFF, P .

TETRAHEDRON LETTERS, 1995, 36 (10) :1589-1592

[7] Solid-phase synthesis of 6-deoxyoligosaccharides [J].

Hunt, JA ;

Roush, WR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (41) :9998-9999

[8] COMPETITIVE CYCLOPROPANATION AND CROSS-METATHESIS REACTIONS OF ALKENES CATALYZED BY DIRUTHENIUM TETRAKIS CARBOXYLATES [J].

NOELS, AF ;

DEMONCEAU, A ;

CARLIER, E ;

HUBERT, AJ ;

MARQUEZSILVA, RL ;

SANCHEZDELGADO, RA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (12) :783-784

[9] SELECTIVE RING-OPENING CROSS-METATHESIS - SHORT SYNTHESES OF MULTIFIDENE AND VIRIDIENE [J].

RANDALL, ML ;

TALLARICO, JA ;

SNAPPER, ML .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (37) :9610-9611

[10] Selective ring-opening olefin metathesis of functionalized monosubstituted olefins [J].

Schneider, MF ;

Lucas, N ;

Velder, J ;

Blechert, S .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (03) :257-259