Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses

被引:40
作者
Badiou, C. [1 ]
Dumitrescu, O. [1 ]
Croze, M. [1 ]
Gillet, Y. [1 ,2 ]
Dohin, B. [3 ]
Slayman, D. H. [4 ]
Allaouchiche, B. [4 ]
Etienne, J. [1 ]
Vandenesch, F. [1 ]
Lina, G. [1 ]
机构
[1] Univ Lyon, INSERM, U851, Ctr Natl Reference Staphylocoques,Fac Laennec, F-69372 Lyon, France
[2] Hosp Civils Lyon, Hop Edouard Herriot, Serv Reanimat Pediat, Lyon, France
[3] Hosp Civils Lyon, Hop Edouard Herriot, Serv Chirurg Pediat, Lyon, France
[4] Hosp Civils Lyon, Hop Edouard Herriot, Dept Anesthesie, Lyon, France
关键词
ELISA; Panton-Valentine leukocidin; quantification; skin infection; Staphylococcus aureus;
D O I
10.1111/j.1469-0691.2008.02105.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Pus samples were prospectively collected from patients with Staphylococcus aureus skin infections and tested for Panton-Valentine leukocidin (PVL). PVL was detected at concentrations that were toxic for rabbit skin in all specimens from patients infected with strains harbouring PVL genes.
引用
收藏
页码:1180 / 1183
页数:4
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