Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses

被引：40

作者：

Badiou, C. ^{[1
]}

Dumitrescu, O. ^{[1
]}

Croze, M. ^{[1
]}

Gillet, Y. ^{[1
,2
]}

Dohin, B. ^{[3
]}

Slayman, D. H. ^{[4
]}

Allaouchiche, B. ^{[4
]}

Etienne, J. ^{[1
]}

Vandenesch, F. ^{[1
]}

Lina, G. ^{[1
]}

机构：

[1] Univ Lyon, INSERM, U851, Ctr Natl Reference Staphylocoques,Fac Laennec, F-69372 Lyon, France

[2] Hosp Civils Lyon, Hop Edouard Herriot, Serv Reanimat Pediat, Lyon, France

[3] Hosp Civils Lyon, Hop Edouard Herriot, Serv Chirurg Pediat, Lyon, France

[4] Hosp Civils Lyon, Hop Edouard Herriot, Dept Anesthesie, Lyon, France

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷 / 12期

关键词：

ELISA; Panton-Valentine leukocidin; quantification; skin infection; Staphylococcus aureus;

D O I：

10.1111/j.1469-0691.2008.02105.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Pus samples were prospectively collected from patients with Staphylococcus aureus skin infections and tested for Panton-Valentine leukocidin (PVL). PVL was detected at concentrations that were toxic for rabbit skin in all specimens from patients infected with strains harbouring PVL genes.

引用

页码：1180 / 1183

页数：4

共 12 条

[11] Is panton-valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? [J].

Voyich, Jovanka M. ;

Otto, Michael ;

Mathema, Barun ;

Braughton, Kevin R. ;

Whitney, Adeline R. ;

Welty, Diane ;

Long, R. Daniel ;

Dorward, David W. ;

Gardner, Donald J. ;

Lina, Gerard ;

Kreiswirth, Barry N. ;

DeLeo, Frank R. .

JOURNAL OF INFECTIOUS DISEASES, 2006, 194 (12) :1761-1770

[12]

WARD PD, 1980, INFECT IMMUN, V28, P393

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