Reduction of carbonyl compounds by using polymethylhydrosiloxane: Reactivity and selectivity

被引：70

作者：

Kobayashi, Y

Takahisa, E

Nakano, M

Watatani, K

机构：

[1] Dept. of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama 226, 4259 Nagatsuta-cho, Midori-ku

来源：

TETRAHEDRON | 1997年 / 53卷 / 05期

关键词：

D O I：

10.1016/S0040-4020(96)01092-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of aldehydes and ketones with PMHS [Me(3)SiO-(SiMe(H)O)(n)-SiMe(3)] proceeded smoothly in the presence of Bu(4)NF at similar to 70 degrees C or 0 degrees C within 60 min in THF. High stereo- and chemoselectivities as well as functional group tolerance of this system are also presented. (C) 1997, Elsevier Science Ltd.

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页码：1627 / 1634

页数：8

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