Research on Preparation and Biological Properties of Dense Hydroxyapatite Spheres

被引:4
作者
Luo Hui-Tao [1 ]
Zhi Wei [1 ]
Lu Xiong [1 ]
Li Jin-Yu [1 ]
Feng Bo [1 ]
Weng Jie [1 ]
机构
[1] Southwest Jiaotong Univ, Sch Mat Sci & Engn, Minist Educ, Key Lab Adv Technol Mat, Chengdu 610031, Peoples R China
关键词
hydroxyapatite; Sol-Gel method; high strength; density; biological property; MECHANICAL-PROPERTIES; MICROSPHERES; TEMPERATURE; BEHAVIOR; POWDER;
D O I
10.3724/SP.J.1077.2013.12038
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
081705 [工业催化]; 082905 [生物质能源与材料];
摘要
By using carboxy methyl chitosan (CMCS) and gelatin (Gel) as adhesive, the nano-HA slurry which was fabricated via a precipitation process as the raw material, dense HA spheres with a uniform size distribution and good geometry were prepared successfully by means of Sol-Gel method. Dense HA spheres with a porosity of 4.7%+/- 0.6% have a higher compressive strength (8.9 +/- 0.4) MPa than that of porous HA spheres (7.9 +/- 0.2) MPa with a porosity of 16.4%+/- 0.5% (particles with diameter of 0.5 mm). The results of biomimetic mineralization and cell culture show that dense HA spheres have an excellent biological property.
引用
收藏
页码:40 / 44
页数:5
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