Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results

被引:11
作者
Hsiung, CY
Hunt, MA
Yorke, ED
Chui, CS
Hu, J
Xiong, JP
Ling, CC
Lo, SK
Wang, CJ
Huang, EY
Amols, HI
机构
[1] Chang Gung Mem Hosp Kaohsiung, Dept Radiat Oncol, Niao Sung Hsian, Kaohsiung Hsien, Taiwan
[2] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10021 USA
[3] Univ Sydney, Inst Int Hlth, Sydney, NSW 2006, Australia
关键词
nasopharyngeal carcinoma; intensity-modulated radiotherapy; inverse planning; optimization; anatomic factor;
D O I
10.1016/j.radonc.2005.04.017
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry. (C) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:53 / 57
页数:5
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