Who comes first?: How plant pathogenic bacteria orchestrate type III secretion

被引:87
作者
Büttner, D [1 ]
Bonas, U [1 ]
机构
[1] Univ Halle Wittenberg, Inst Genet, D-06099 Halle, Germany
关键词
D O I
10.1016/j.mib.2006.02.006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The type III secretion system (T3SS) is a key pathogenicity factor of many Gram-negative plant and animal pathogens and is also present in some symbiotic bacteria. T3SSs are highly conserved, complex molecular injection machines that translocate bacterial effector proteins directly into eukaryotic cells. Recent genetic, biochemical and structural studies revealed that the activity of the T3SS is regulated by common mechanisms in different bacterial species. In many cases, type III secretion is activated upon host cell contact and depends on specific control proteins, including transcriptional regulators and type III secretion chaperones.
引用
收藏
页码:193 / 200
页数:8
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