Pulmonary Complications of Sickle Cell Disease.

被引:310
作者
Gladwin, Mark T. [1 ,2 ]
Vichinsky, Elliott [3 ]
机构
[1] Univ Pittsburgh, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Hemostasis & Vasc Biol Res Inst, Pittsburgh, PA 15213 USA
[3] Childrens Hosp & Res Ctr, Oakland, CA USA
关键词
D O I
10.1056/NEJMra0804411
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review presents evidence for two overlapping yet distinctive clinical types of sickle cell disease. The basis of one is the vaso-occlusive crisis; the other is the consequence of intravascular hemolysis. The authors focus on the acute vaso-occlusive crisis, the acute chest syndrome, and pulmonary hypertension, all common complications of sickle cell disease. Copyright © 2008 Massachusetts Medical Society.
引用
收藏
页码:2254 / 2265
页数:12
相关论文
共 124 条
  • [1] PULMONARY-HYPERTENSION AND RIGHT HEART-FAILURE IN PATIENTS WITH BETA-THALASSEMIA-INTERMEDIA
    AESSOPOS, A
    STAMATELOS, G
    SKOUMAS, V
    VASSILOPOULOS, G
    MANTZOURANI, M
    LOUKOPOULOS, D
    [J]. CHEST, 1995, 107 (01) : 50 - 53
  • [2] Cardiac involvement in thalassemia intermedia: a multicenter study
    Aessopos, A
    Farmakis, D
    Karagiorga, M
    Voskaridou, E
    Loutradi, A
    Hatziliami, A
    Joussef, J
    Rombos, J
    Loukopoulos, D
    [J]. BLOOD, 2001, 97 (11) : 3411 - 3416
  • [3] Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria
    Aliyu, Zakari Y.
    Gordeuk, Victor
    Sachdev, Vandana
    Babadoko, Aliyu
    Mamman, Aisha I.
    Akpanpe, Peter
    Attah, Ester
    Suleiman, Yusuf
    Aliyu, Nurudeen
    Yusuf, Jamilu
    Mendelsohn, Laurel
    Kato, Gregory J.
    Gladwin, Mark T.
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 2008, 83 (06) : 485 - 490
  • [4] Elevation of tricuspid regurgitant jet velocity, a marker for pulmonary hypertension in children with sickle cell disease
    Ambrusko, Steven J.
    Gunawardena, Sriya
    Sakara, Allison
    Windsor, Beth
    Lanford, Lizabeth
    Michelson, Peter
    Krishnamurti, Lakshmanan
    [J]. PEDIATRIC BLOOD & CANCER, 2006, 47 (07) : 907 - 913
  • [5] Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension
    Anthi, Anastasia
    Machado, Roberto F.
    Jison, Maria L.
    Taveira-DaSilva, Angelo M.
    Rubin, Lewis J.
    Hunter, Lori
    Hunter, Christian J.
    Coles, Wynona
    Nichols, James
    Avila, Nilo A.
    Sachdev, Vandana
    Chen, Clara C.
    Gladwin, Mark T.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 175 (12) : 1272 - 1279
  • [6] Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease
    Aslan, M
    Ryan, TM
    Adler, B
    Townes, TM
    Parks, DA
    Thompson, JA
    Tousson, A
    Gladwin, MT
    Patel, RP
    Tarpey, MM
    Batinic-Haberle, I
    White, CR
    Freeman, BA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) : 15215 - 15220
  • [7] Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension
    Ataga, Kenneth, I
    Moore, Charity G.
    Hillery, Cheryl A.
    Jones, Susan
    Whinna, Herbert C.
    Strayhorn, Dell
    Sohier, Cathy
    Hinderliter, Alan
    Parise, Leslie, V
    Orringer, Eugene P.
    [J]. HAEMATOLOGICA, 2007, 93 (01) : 20 - 26
  • [8] Pulmonary hypertension in patients with sickle cell disease: a longitudinal study
    Ataga, Kenneth I.
    Moore, Charity G.
    Jones, Susan
    Olajide, Oludamilola
    Strayhorn, Dell
    Hinderliter, Alan
    Orringer, Eugene P.
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2006, 134 (01) : 109 - 115
  • [9] Pulmonary hypertension in sickle cell disease
    Ataga, KI
    Sood, N
    De Gent, G
    Kelly, E
    Henderson, AG
    Jones, S
    Strayhorn, D
    Lail, A
    Lieff, S
    Orringer, EP
    [J]. AMERICAN JOURNAL OF MEDICINE, 2004, 117 (09) : 665 - 669
  • [10] Biliverdin reductase:: A major physiologic cytoprotectant
    Barañano, DE
    Rao, M
    Ferris, CD
    Snyder, SH
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (25) : 16093 - 16098