Pulmonary Complications of Sickle Cell Disease.

被引:310
作者
Gladwin, Mark T. [1 ,2 ]
Vichinsky, Elliott [3 ]
机构
[1] Univ Pittsburgh, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Hemostasis & Vasc Biol Res Inst, Pittsburgh, PA 15213 USA
[3] Childrens Hosp & Res Ctr, Oakland, CA USA
关键词
D O I
10.1056/NEJMra0804411
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review presents evidence for two overlapping yet distinctive clinical types of sickle cell disease. The basis of one is the vaso-occlusive crisis; the other is the consequence of intravascular hemolysis. The authors focus on the acute vaso-occlusive crisis, the acute chest syndrome, and pulmonary hypertension, all common complications of sickle cell disease. Copyright © 2008 Massachusetts Medical Society.
引用
收藏
页码:2254 / 2265
页数:12
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