A prototype device for evaporation in batch and flow chemical processes

被引:61
作者
Deadman, Benjamin J. [1 ]
Battilocchio, Claudio [1 ]
Sliwinski, Eric [1 ]
Ley, Steven V. [1 ]
机构
[1] Univ Cambridge, Dept Chem, Innovat Technol Ctr, Cambridge CB2 1EW, England
基金
英国工程与自然科学研究理事会;
关键词
CHEMISTRY; CATALYSTS; MECHANISM; ALDEHYDES; SILICA; AMINE; GREEN;
D O I
10.1039/c3gc40967h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a convenient and efficient prototype device for evaporating, concentrating and switching solvents in continuous flow and batch processing and batch mode fashion. One of the main features of this system is the level of recyclability, whereby all solvents removed can be easily collected and reused, with reduced environmental impact.
引用
收藏
页码:2050 / 2055
页数:6
相关论文
共 51 条
[1]   Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation [J].
Alfonsi, Kim ;
Colberg, Juan ;
Dunn, Peter J. ;
Fevig, Thomas ;
Jennings, Sandra ;
Johnson, Timothy A. ;
Kleine, H. Peter ;
Knight, Craig ;
Nagy, Mark A. ;
Perry, David A. ;
Stefaniak, Mark .
GREEN CHEMISTRY, 2008, 10 (01) :31-36
[2]  
[Anonymous], 53170 DIN
[3]   Use of heterogeneous catalyst KG-60-NEt2 in Michael and Henry reactions involving nitroalkanes [J].
Ballini, R ;
Bosica, G ;
Livi, D ;
Palmieri, A ;
Maggi, R ;
Sartori, G .
TETRAHEDRON LETTERS, 2003, 44 (11) :2271-2273
[4]   A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1 [J].
Battilocchio, Claudio ;
Deadman, Benjamin J. ;
Nikbin, Nikzad ;
Kitching, Matthew O. ;
Baxendale, Ian R. ;
Ley, Steven V. .
CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (24) :7917-7930
[5]   A Mild and Efficient Flow Procedure for the Transfer Hydrogenation of Ketones and Aldehydes using Hydrous Zirconia [J].
Battilocchio, Claudio ;
Hawkins, Joel M. ;
Ley, Steven V. .
ORGANIC LETTERS, 2013, 15 (09) :2278-2281
[6]   A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid [J].
Battilocchio, Claudio ;
Baxendale, Ian R. ;
Biava, Mariangela ;
Kitching, Matthew O. ;
Ley, Steven V. .
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2012, 16 (05) :798-810
[7]   Continuous flow reaction monitoring using an on-line miniature mass spectrometer [J].
Browne, Duncan L. ;
Wright, Steven ;
Deadman, Benjamin J. ;
Dunnage, Samantha ;
Baxendale, Ian R. ;
Turner, Richard M. ;
Ley, Steven V. .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2012, 26 (17) :1999-2010
[8]   Base supported ionic liquid-like phases as catalysts for the batch and continuous-flow Henry reaction [J].
Burguete, M. Isabel ;
Erythropel, Hanno ;
Garcia-Verdugo, Eduardo ;
Luis, Santiago V. ;
Sans, Victor .
GREEN CHEMISTRY, 2008, 10 (04) :401-407
[9]   ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing [J].
Carter, Catherine F. ;
Lange, Heiko ;
Ley, Steven V. ;
Baxendale, Ian R. ;
Wittkamp, Brian ;
Goode, Jon G. ;
Gaunt, Nigel L. .
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2010, 14 (02) :393-404
[10]   Microfluidic evaporator for on-chip sample concentration [J].
Casadevall i Solvas, Xavier ;
Turek, Vladimir ;
Prodromakis, Themistoklis ;
Edel, Joshua B. .
LAB ON A CHIP, 2012, 12 (20) :4049-4054