Untimely ends and new beginnings in mouse cloning

被引：24

作者：

Perry, ACF

Wakayama, T

机构：

[1] Adv Cell Technol, Worcester, MA 01605 USA

[2] Ctr Dev Biol, Chuo Ku, Kobe, Hyogo 6500047, Japan

来源：

NATURE GENETICS | 2002年 / 30卷 / 03期

关键词：

D O I：

10.1038/ng0302-243

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A new study shows that the majority of mice cloned from somatic cells die prematurely. Of the six dead clones analyzed, four exhibited extensive necrosis of the liver, two had tumors and all had pneumonia, suggestive of immune impairment. These latest cloning-associated phenotypes will facilitate a better understanding of the mechanisms underlying nuclear-transfer cloning in mammals.

引用

页码：243 / 244

页数：2

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