Emerging technologies in DNA sequencing

被引：279

作者：

Metzker, ML ^{[1
]}

机构：

[1] Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA

来源：

GENOME RESEARCH | 2005年 / 15卷 / 12期

关键词：

D O I：

10.1101/gr.3770505

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Demand for DNA sequence information has never been greater, yet current Sanger technology is too costly, time consuming, and labor intensive to meet this ongoing demand. Applications span numerous research interests, including sequence variation studies, comparative genomics and evolution, forensics, and diagnostic and applied therapeutics. Several emerging technologies show promise of delivering next-generation Solutions for fast and affordable genome sequencing. In this review article, the DNA polymerase-dependent strategies of Sanger sequencing, single nucleotide addition, and cyclic reversible termination are discussed to highlight recent advances and potential challenges these technologies face in their development for ultrafast DNA sequencing.

引用

页码：1767 / 1776

页数：10

共 109 条

[21] Dispersion sources for compact geometries on microchips
Culbertson, CT
Jacobson, SC
Ramsey, JM
[J]. ANALYTICAL CHEMISTRY, 1998, 70 (18) : 3781 - 3789
[22] High-resolution haplotype structure in the human genome
Daly, MJ
Rioux, JD
Schaffner, SE
Hudson, TJ
Lander, ES
[J]. NATURE GENETICS, 2001, 29 (02) : 229 - 232
[23] New strategies for efficient typing of HLA class-II loci DQB1 and DRB1 by using Pyrosequencing™
Entz, P
Toliat, MR
Hampe, J
Valentonyte, R
Jenisch, S
Nürnberg, P
Nagy, M
[J]. TISSUE ANTIGENS, 2005, 65 (01): : 67 - 80
[24] Base-calling of automated sequencer traces using phred.: II.: Error probabilities
Ewing, B
Green, P
[J]. GENOME RESEARCH, 1998, 8 (03): : 186 - 194
[25] Base-calling of automated sequencer traces using phred.: I.: Accuracy assessment
Ewing, B
Hillier, L
Wendl, MC
Green, P
[J]. GENOME RESEARCH, 1998, 8 (03): : 175 - 185
[26] The ENCODE (ENCyclopedia of DNA elements) Project
Feingold, EA
Good, PJ
Guyer, MS
Kamholz, S
Liefer, L
Wetterstrand, K
Collins, FS
Gingeras, TR
Kampa, D
Sekinger, EA
Cheng, J
Hirsch, H
Ghosh, S
Zhu, Z
Pate, S
Piccolboni, A
Yang, A
Tammana, H
Bekiranov, S
Kapranov, P
Harrison, R
Church, G
Struhl, K
Ren, B
Kim, TH
Barrera, LO
Qu, C
Van Calcar, S
Luna, R
Glass, CK
Rosenfeld, MG
Guigo, R
Antonarakis, SE
Birney, E
Brent, M
Pachter, L
Reymond, A
Dermitzakis, ET
Dewey, C
Keefe, D
Denoeud, F
Lagarde, J
Ashurst, J
Hubbard, T
Wesselink, JJ
Castelo, R
Eyras, E
Myers, RM
Sidow, A
Batzoglou, S
[J]. SCIENCE, 2004, 306 (5696) : 636 - 640
[27] Race, ethnicity, and genomics: Social classifications as proxies of biological heterogeneity
Foster, MW
Sharp, RR
[J]. GENOME RESEARCH, 2002, 12 (06) : 844 - 850
[28] FOX MS, 1990, SCIENCE, V247, P270
[29] The structure of haplotype blocks in the human genome
Gabriel, SB
Schaffner, SF
Nguyen, H
Moore, JM
Roy, J
Blumenstiel, B
Higgins, J
DeFelice, M
Lochner, A
Faggart, M
Liu-Cordero, SN
Rotimi, C
Adeyemo, A
Cooper, R
Ward, R
Lander, ES
Daly, MJ
Altshuler, D
[J]. SCIENCE, 2002, 296 (5576) : 2225 - 2229
[30] Long-read pyrosequencing using pure 2′-deoxyadenosine-5′-O′-(1-thiotriphosphate) Sp-isomer
Gharizadeh, B
Nordström, T
Ahmadian, A
Ronaghi, M
Nyrén, P
[J]. ANALYTICAL BIOCHEMISTRY, 2002, 301 (01) : 82 - 90

← 1 2 3 4 5 6 7 8 9 10 →