Bactericidal activity of trovafloxacin (CP-99,219)

被引：16

作者：

Morrissey, I ^{[1
]}

机构：

[1] UNIV E LONDON,CHEMOTHERAPY RES UNIT,LONDON E15 4LZ,ENGLAND

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1996年 / 38卷 / 06期

关键词：

D O I：

10.1093/jac/38.6.1061

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Trovafloxacin was found to be a typical quinolone producing a biphasic dose response against Escherichia coli, Staphylococcus aureus or Streptococcus pneumoniae. A reduced rate of kill was seen against Enterococcus faecalis, which is also typical of the quinolones. However, the bactericidal activity of trovafloxacin against S. aureus and S. pneumoniae was greater than most other quinolones previously tested. The enhanced bactericidal activity of trovafloxacin against S. aureus may be explained by the possession of a very strong bactericidal mechanism B. Trovafloxacin may prove to be a quinolone of choice against S. aureus infections.

引用

页码：1061 / 1066

页数：6

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