Amidine protection for solution phase library synthesis

被引：11

作者：

Bailey, C ^{[1
]}

Baker, E ^{[1
]}

Hayler, J ^{[1
]}

Kane, P ^{[1
]}

机构：

[1] Novartis Horsham Res Ctr, Horsham RH12 4AB, W Sussex, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(99)00891-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of 4-methoxybenzyl-4-nitrophenylcarbonate as a reagent for the N-protection of amidinonaphthol has been demonstrated. The facile introduction of the 4-methoxybenzyloxycarbonyl group and the mildness of the deprotection conditions make this reagent well suited for the multiparallel solution phase synthesis of substituted benzamidines. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4847 / 4850

页数：4

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