Optimization of electron-capture detector when using packed-column supercritical fluid chromatography with modified carbon dioxide

被引：11

作者：

Strode, JTB ^{[1
]}

Taylor, LT ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM,BLACKSBURG,VA 24061

来源：

JOURNAL OF CHROMATOGRAPHY A | 1996年 / 723卷 / 02期

关键词：

detectors; SFC; electron capture detector; phenylureas; pesticides; nitrogen-containing compounds; propellants;

D O I：

10.1016/0021-9673(95)00859-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Response surfaces were obtained for packed-column supercritical fluid chromatography with electron-capture detection (SFC-ECD) under various detector conditions to optimize the ECD for use with modified CO2. Limits of detection, correlation coefficients and linear dynamic ranges were found to vary with increasing amounts of modifier for several nitrogen-containing and halogenated compounds. Low detection limits (pg) were achieved in the presence of 5% methanol-modified CO2. Applications of packed-column SFC-ECD to the separation of nitrogen-containing compounds extracted from propellants and phenylurea herbicides are presented.

引用

页码：361 / 369

页数：9

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