Is action potential threshold lowest in the axon?

被引:114
作者
Kole, Maarten H. P. [1 ]
Stuart, Greg J. [1 ]
机构
[1] Australian Natl Univ, Div Neurosci, John Curtin Sch Med Res, Canberra, ACT 0200, Australia
基金
英国医学研究理事会;
关键词
D O I
10.1038/nn.2203
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Action potential threshold is thought to be lowest in the axon, but when measured using conventional techniques, we found that action potential voltage threshold of rat cortical pyramidal neurons was higher in the axon than at other neuronal locations. In contrast, both current threshold and voltage threshold of the isolated somato-dendritic spike were substantially higher at the soma. These data indicate that action potential threshold is indeed lowest in the axon.
引用
收藏
页码:1253 / 1255
页数:3
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