Iron-catalysed Negishi coupling of benzyl halides and phosphates

被引：153

作者：

Bedford, Robin B. ^{[1
]}

Huwe, Michael ^{[1
]}

Wilkinson, Mark C. ^{[2
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

[2] GlaxoSmithKline Inc, Chem Dev, Stevenage SG1 2NY, Herts, England

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 05期

基金：

英国工程与自然科学研究理事会;

关键词：

ARYL GRIGNARD-REAGENTS; SECONDARY ALKYL-HALIDES; BEARING BETA-HYDROGENS; DIHYDROFOLATE-REDUCTASE; ARYLBORONIC ACIDS; PNEUMOCYSTIS-CARINII; ARYLMAGNESIUM REAGENTS; MYCOBACTERIUM-AVIUM; TOXOPLASMA-GONDII; INHIBITORS;

D O I：

10.1039/b818961g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iron-based catalysts containing either 1,2-bis(diphenylphosphino)benzene or 1,3-bis(diphenylphosphino)propane give excellent activity and good selectivity in the Negishi coupling of aryl zinc reagents with a range of benzyl halides and phosphates.

引用

页码：600 / 602

页数：3

共 36 条

[1] MOSSBAUER AND PREPARATIVE STUDIES OF SOME IRON(II) COMPLEXES OF DIPHOSPHINES
BARCLAY, JE
LEIGH, GJ
HOULTON, A
SILVER, J
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1988, (11): : 2865 - 2870
[2] Iron nanoparticles in the coupling of alkyl halides with aryl Grignard reagents
Bedford, RB
Betham, M
Bruce, DW
Davis, SA
Frost, RM
Hird, M
[J]. CHEMICAL COMMUNICATIONS, 2006, (13) : 1398 - 1400
[3] Iron-phosphine, -phosphite, -arsine, and -carbene catalysts for the coupling of primary and secondary 2 alkyl halides with aryl Grignard reagents
Bedford, RB
Betham, M
Bruce, DW
Danopoulos, AA
Frost, RM
Hird, M
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (03) : 1104 - 1110
[4] Iron(III) salen-type catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing β-hydrogens
Bedford, RB
Bruce, DW
Frost, RM
Goodby, JW
Hird, M
[J]. CHEMICAL COMMUNICATIONS, 2004, (24) : 2822 - 2823
[5] Simple iron-amine catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing β-hydrogens
Bedford, RB
Bruce, DW
Frost, RM
Hird, M
[J]. CHEMICAL COMMUNICATIONS, 2005, (33) : 4161 - 4163
[6] An iron-containing ionic liquid as recyclable catalyst for aryl grignard cross-coupling of alkyl halides
Bica, K
Gaertner, P
[J]. ORGANIC LETTERS, 2006, 8 (04) : 733 - 735
[7] Iron-catalyzed reactions in organic synthesis
Bolm, C
Legros, J
Le Paih, J
Zani, L
[J]. CHEMICAL REVIEWS, 2004, 104 (12) : 6217 - 6254
[8] Iron catalyzed polyethylene chain growth on zinc:: A study of the factors delineating chain transfer versus catalyzed chain growth in zinc and related metal alkyl systems
Britovsek, GJP
Cohen, SA
Gibson, VC
van Meurs, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (34) : 10701 - 10712
[9] Simple palladium(II) precatalyst for Suzuki-Miyaura couplings: Efficient reactions of benzylic, aryl, heteroaryl, and vinyl coupling partners
Burns, Michael J.
Fairlamb, Ian J. S.
Kapdi, Anant R.
Sehnal, Petr
Taylor, Richard J. K.
[J]. ORGANIC LETTERS, 2007, 9 (26) : 5397 - 5400
[10] Iron-catalyzed alkylation of alkenyl Grignard reagents
Cahiez, Gerard
Duplais, Christophe
Moyeux, Alban
[J]. ORGANIC LETTERS, 2007, 9 (17) : 3253 - 3254

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