A DAST-free route to aryl(difluoromethyl)phosphonic esters

被引：15

作者：

Blades, K

Cockerill, GS

Easterfield, HJ

Lequeux, TP

Percy, JM

机构：

[1] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

[2] GLAXO WELLCOME RES & DEV LTD,STEVENAGE SG1 2NY,HERTS,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 14期

关键词：

D O I：

10.1039/cc9960001615

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The cerium(III)-mediated addition of diethyl (lithiodifluoromethyl)phosphonate to a benzoquinone monoketal allows the synthesis of phenol bearing the (diethoxyphosphonyl)difluoromethyl group via short, scaleable reaction sequences which avoid the use of the DAST reagent.

引用

页码：1615 / 1616

页数：2

共 21 条

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