The 10-s maximal sprint - A novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes

被引:106
作者
Bussau, VA
Ferreira, LD
Jones, TW
Fournier, PA
机构
[1] Univ Western Australia, Sch Human Movement & Exercise Sci, Crawley, WA 6009, Australia
[2] Princess Margaret Hosp, Dept Endocrinol, Subiaco, WA, Australia
[3] Univ Western Australia, Telethon Inst Child Hlth Res, Ctr Child Hlth Res, Perth, WA 6009, Australia
关键词
D O I
10.2337/diacare.29.03.06.dc05-1764
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - To investigate whether a short maximal sprint can provide another means to counter the rapid fall in glycemia associated with moderate-intensity exercise in individuals With type 1 diabetes and therefore decrease the risk of early postexercise hypoglycemia. RESEARCH DESIGN AND METHODS - in the Study, seven male subjects with type 1 diabetes injected their normal insulin dose and ate their usual breakfast. When their postprandial glycemia fell to -11 mmol/l, they pedaled at 40% VO2peak for 20 min on a cycle ergometer then immediately engaged in a maximal 10-s cycling sprint (sprint trial) or tested (control trial); the sprint and rest trials were administered in a counterbalanced order. RESULTS - Moderate-intensity exercise resulted in a significant fall (P < 0.05) in glycemia in both trials (means +/- SE: 3.6 +/- 0.5 vs. 3.1 +/- 0.5 mmol/l for sprint and control, respectively). The subsequent short cycling sprint opposed a further fall in glycemia for 120 min, whereas in the absence of a sprint, glycemia decreased further (3.6 +/- 1.22 mmol/l; P < 0.05) after exercise. The stabilization of glycemia in the sprint trial was associated with elevated levels of catecholamines, growth hormone, and cortisol. In contrast, these hormones remained at stable or near-stable levels in the control trial. Changes in insulin and free fatty acid levels were similar in the sprint and control trials. CONCLUSIONS - These results suggest that after moderate-intensity exercise, it is preferable for young individuals With insulin-treated, complication-free type 1 diabetes to engage in a 10-s maximal sprint to acutely oppose a further fall in glycemia than to only rest. The addition of the sprint after moderate-intensity exercise provides another means to reduce the risk of hypoglycemia in active individuals with type 1 diabetes.
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收藏
页码:601 / 606
页数:6
相关论文
共 28 条
[21]   INFLUENCE OF ACUTE PHYSIOLOGICAL INCREMENTS OF CORTISOL ON FUEL METABOLISM AND INSULIN BINDING TO MONOCYTES IN NORMAL HUMANS [J].
SHAMOON, H ;
SOMAN, V ;
SHERWIN, RS .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1980, 50 (03) :495-501
[22]   Glucoregulation during and after intense exercise:: Effects of β-adrenergic blockade in subjects with type 1 diabetes mellitus [J].
Sigal, RJ ;
Fisher, SJ ;
Halter, JB ;
Vranic, M ;
Marliss, EB .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (11) :3961-3971
[23]   HYPERINSULINEMIA PREVENTS PROLONGED HYPERGLYCEMIA AFTER INTENSE EXERCISE IN INSULIN-DEPENDENT DIABETIC SUBJECTS [J].
SIGAL, RJ ;
PURDON, C ;
FISHER, SJ ;
HALTER, JB ;
VRANIC, M ;
MARLISS, EB .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 79 (04) :1049-1057
[24]   The roles of catecholamines in glucoregulation in intense exercise as defined by the islet cell clamp technique [J].
Sigal, RJ ;
Fisher, S ;
Halter, JB ;
Vranic, M ;
Marliss, EB .
DIABETES, 1996, 45 (02) :148-156
[25]   Physical activity/exercise and type 2 diabetes - A consensus statement from the American diabetes association [J].
Sigal, Ronald J. ;
Kenny, Glen P. ;
Wasserman, David H. ;
Castaneda-Sceppa, Carmen ;
White, Russell D. .
DIABETES CARE, 2006, 29 (06) :1433-1438
[26]  
Telford R., 1987, Excel, V4, P11
[27]  
VANPRAAGH E, 1998, PEDIAT ANAEROBIC PER, P298
[28]   EXERCISE IN INDIVIDUALS WITH IDDM [J].
WASSERMAN, DH ;
ZINMAN, B .
DIABETES CARE, 1994, 17 (08) :924-937