On the tautomerism of 2,1,3-benzothiadiazinone S,S-dioxide and related compounds

被引：6

作者：

Castro, A ^{[1
]}

Gil, C ^{[1
]}

Martínez, A ^{[1
]}

机构：

[1] CSIC, Inst Quim Med, E-28006 Madrid, Spain

来源：

TETRAHEDRON | 1999年 / 55卷 / 42期

关键词：

benzothiazines; tautomerism; theoretical studies; NMR;

D O I：

10.1016/S0040-4020(99)00723-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tautomerism of 2,1,3-benzothiadiazinone 2,2-dioxide and other related fused heterocyclic amides has been studied by means of experimental (H-1- and C-13-NMR) and theoretical (ab initio calculations) techniques. The synthesis and spectroscopic characterization of mono- and di-blocked derivatives was carried out. The results predict that the keto form is the most abundant tautomer in the gas phase, while the N1(H) hydroxy is the preferred one in solution and the solid state. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：12405 / 12410

页数：6

共 20 条

[1]

ALBERT A, 1971, UV DETERMINATION ION

[2] TAUTOMERISM OF NEUTRAL AND PROTONATED 6-THIOGUANINE IN THE GAS-PHASE AND IN AQUEOUS-SOLUTION - AN AB-INITIO STUDY [J].