Obstructive uropathy

被引：44

作者：

Becker, A ^{[1
]}

Baum, M ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Pediat, Dallas, TX 75390 USA

来源：

EARLY HUMAN DEVELOPMENT | 2006年 / 82卷 / 01期

关键词：

vesicoureteral reflux; neonates; antenatal hydronephrosis;

D O I：

10.1016/j.earlhumdev.2005.11.002

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Routine second trimester ultrasound screening has resulted in more infants diagnosed with antenatal hydronephrosis. Current recommendations suggest postnatal evaluation of all infants with a renal pelvic diameter >5 mm with ultrasound and voiding cystourethrogram (VCUG.) There are many etiologies of obstructive uropathy including ureteropelvic junction (UPJ) obstruction, ureterovesical junction (UVJ) obstruction, posterior urethral. valves (PUV), prune belly syndrome, and vesicoureteral reflux (VUR). Obstructive uropathy can result in tubular damage and decreased nephron number. Tubular damage can result in sodium wasting, hyperkalemic acidosis, and nephrogenic diabetes insipidus. Most patients do not require renal replacement therapy in the neonatal period; however, chronic renal insufficiency can occur if the neonate has a significant reduction in nephron number or progressive renal damage from obstruction or infection. (C) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：15 / 22

页数：8

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